Hua Su Selected Research

Arteriovenous Malformations (Arteriovenous Malformation)

1/2022	Bone Marrow-Derived Alk1 Mutant Endothelial Cells and Clonally Expanded Somatic Alk1 Mutant Endothelial Cells Contribute to the Development of Brain Arteriovenous Malformations in Mice.
1/2021	Proof-of-concept single-arm trial of bevacizumab therapy for brain arteriovenous malformation.
4/2019	Effect of elevation of vascular endothelial growth factor level on exacerbation of hemorrhage in mouse brain arteriovenous malformation.
1/2018	Thalidomide Reduces Hemorrhage of Brain Arteriovenous Malformations in a Mouse Model.
10/2017	Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages.
3/2014	De novo cerebrovascular malformation in the adult mouse after endothelial Alk1 deletion and angiogenic stimulation.
1/2014	Distinctive distribution of lymphocytes in unruptured and previously untreated brain arteriovenous malformation.
2/2013	Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.
7/2012	Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue.
7/2012	Bevacizumab attenuates VEGF-induced angiogenesis and vascular malformations in the adult mouse brain.

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Hua Su Research Topics

Disease

31	Neoplasms (Cancer) 09/2022 - 07/2003
15	Arteriovenous Malformations (Arteriovenous Malformation) 01/2022 - 12/2008
11	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 11/2014
11	Stroke (Strokes) 01/2021 - 04/2010
10	Hemorrhage 06/2022 - 07/2011
10	Hypoxia (Hypoxemia) 01/2020 - 07/2002
9	Inflammation (Inflammations) 05/2022 - 07/2012
9	Esophageal Squamous Cell Carcinoma 03/2022 - 01/2003
8	Infarction (Infarctions) 01/2021 - 11/2004
8	Hereditary Hemorrhagic Telangiectasia 01/2020 - 12/2008
7	Fibrosis (Cirrhosis) 10/2021 - 09/2009
7	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 01/2017
6	COVID-19 01/2021 - 01/2020
6	Adenocarcinoma 01/2021 - 10/2011
6	Proteinuria 01/2020 - 01/2015
6	Ischemic Stroke 12/2017 - 01/2013
5	Lung Neoplasms (Lung Cancer) 01/2022 - 10/2009
4	Infections 01/2021 - 11/2004
4	Atrophy 01/2021 - 04/2010
4	Starvation 01/2021 - 04/2014
4	Pulmonary Hypertension 01/2020 - 03/2016
4	Chronic Renal Insufficiency 01/2020 - 01/2017
4	Type 2 Diabetes Mellitus (MODY) 01/2019 - 10/2008
4	Bone Fractures (Bone Fracture) 12/2017 - 06/2013
4	Stomach Neoplasms (Stomach Cancer) 02/2016 - 01/2013
4	Brain Injuries (Brain Injury) 11/2014 - 10/2006
4	Ischemia 10/2011 - 01/2003
3	Obesity 01/2022 - 10/2008
3	Vascular Malformations 01/2022 - 07/2012
3	Wounds and Injuries (Trauma) 01/2021 - 03/2013
3	Carcinogenesis 01/2021 - 06/2008
3	Kidney Diseases (Kidney Disease) 01/2020 - 01/2017
3	Rupture 04/2019 - 03/2009
3	Chronic Kidney Failure (Chronic Renal Failure) 01/2019 - 01/2015
3	Hyperglycemia 01/2017 - 01/2015
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2017 - 11/2011
3	Myocardial Infarction 01/2012 - 09/2009
2	Encephalitis (Encephalitis, Rasmussen) 08/2022 - 10/2012
2	Sepsis (Septicemia) 05/2022 - 01/2014
2	Adenocarcinoma of Lung 01/2022 - 01/2021
2	Fatty Liver 01/2022 - 12/2021
2	Vascular Remodeling 03/2021 - 07/2009
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 01/2021
2	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2021
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2019
2	Neuroinflammatory Diseases 01/2021 - 11/2014
2	Fatigue 01/2020 - 01/2018
2	Necrosis 01/2020 - 09/2004
2	Hypertension (High Blood Pressure) 04/2019 - 01/2018

Drug/Important Bio-Agent (IBA)

22	Proteins (Proteins, Gene)FDA Link 12/2021 - 04/2003
15	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2019 - 07/2002
8	EndoglinIBA 01/2022 - 07/2009
8	Activin Receptors (Activin Receptor)IBA 01/2022 - 12/2008
8	Messenger RNA (mRNA)IBA 05/2020 - 09/2004
7	CytokinesIBA 05/2022 - 09/2004
7	RNA (Ribonucleic Acid)IBA 01/2021 - 09/2004
6	Biomarkers (Surrogate Marker)IBA 05/2020 - 06/2008
5	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2021 - 01/2014
5	InflammasomesIBA 01/2021 - 11/2014
5	MicroRNAs (MicroRNA)IBA 05/2020 - 08/2015
4	DNA (Deoxyribonucleic Acid)IBA 03/2022 - 01/2003
4	Pharmaceutical PreparationsIBA 01/2020 - 10/2018
4	cresyl violetIBA 02/2019 - 10/2006
4	Interleukin-6 (Interleukin 6)IBA 02/2019 - 03/2009
4	LipidsIBA 01/2019 - 01/2018
3	Neutralizing AntibodiesIBA 08/2022 - 10/2012
3	VaccinesIBA 08/2022 - 03/2009
3	EnzymesIBA 01/2021 - 09/2012
3	Biological ProductsIBA 01/2021 - 10/2019
3	Claudin-5IBA 11/2020 - 12/2017
3	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 06/2016
3	CreatinineIBA 01/2020 - 01/2019
3	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2019 - 01/2015
3	ErbB Receptors (EGF Receptor)IBA 01/2017 - 11/2009
3	Vitamin D FDA LinkGeneric 02/2016 - 09/2012
3	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2016 - 01/2015
3	ThioredoxinsIBA 01/2016 - 11/2014
3	PolyethyleneimineIBA 01/2015 - 01/2013
3	Small Interfering RNA (siRNA)IBA 01/2015 - 01/2013
2	Ethanol (Ethyl Alcohol)IBA 09/2022 - 12/2021
2	6-methyladenineIBA 01/2022 - 01/2020
2	Mitogen-Activated Protein KinasesIBA 01/2022 - 12/2021
2	CollagenIBA 10/2021 - 01/2021
2	Therapeutic UsesIBA 10/2021 - 09/2009
2	Transcription Factors (Transcription Factor)IBA 10/2021 - 06/2009
2	Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA 03/2021 - 01/2018
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2021 - 01/2018
2	Bevacizumab (Avastin)FDA Link 01/2021 - 07/2012
2	PHA-568487EIBA 01/2021 - 11/2014
2	Amino Acids FDA Link 01/2021 - 12/2015
2	AlbuminsIBA 01/2021 - 01/2018
2	salicylhydroxamic acid (SHAM)IBA 11/2020 - 01/2020
2	Nucleic AcidsIBA 10/2020 - 01/2020
2	AntibodiesIBA 10/2020 - 01/2020
2	N-acetyltalosaminuronic acid (NAT)IBA 10/2020 - 01/2020
2	CopperIBA 06/2020 - 04/2010

Therapy/Procedure

23	Therapeutics 01/2022 - 10/2006
3	Punctures 06/2022 - 07/2019
3	Drug Therapy (Chemotherapy) 01/2021 - 01/2015
3	Renal Dialysis (Hemodialysis) 10/2020 - 01/2018